Typing: Molecular surveillance of MDR in Europe – call for action
Antimicrobial resistance has been declared the largest threat to humans worldwide, with an estimation of 10 Million deaths by 2050 (WHO, 2014). Multidrug resistance (MDR) bacteria, mostly species that are healthcare-associated and part of the human microbiota, are challenging healthcare institutions in many different ways. The occurrences of carbapenemase-producing Enterobacteriaceae (CPE) are the most emerging threat, especially since they are also frequently resistant to many other antibiotics than carbapenems leaving few treatment options. The extent, to which healthcare systems have already been affected, however, differs substantially from country to country. The objective of this talk is to introduce the European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) project and elaborate on the specific steps taken to establish a network of laboratories for active molecular surveillance in 36 countries in Europe. The exection and final results of the prospective multinational structured survey on the occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals will be presented with focus on the molecular surveillance aspect to prevent and control the spread of CPE in Europe.