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 FACULTY
Adrian Egli
Claudio Köser
Sarah Tschudin-Sutter
Stefan Niemann
Helena Seth-Smith
Veronika Boskova
Richard Neher
Corinna Glasner
Aitana Lebrand
John Rossen
Christian Beisel
Joao André Carrico

SARAH TSCHUDIN-SUTTER

University Hospital Basel, Switzerland

What the Hospital Epidemiologist needs to know about NGS…




 

Abstract

In contrast to conventional typing methodologies, next generation sequencing enables to track outbreaks and transmission chains at much higher resolution, facilitating the identification of sources and reservoirs across institutions, countries and continents. Possible identification of mobile genetic elements, such as plasmids, may reveal additional transmission events, which may have been missed previously, thus leading to the detection of additional transmission pathways. The increasing availability and abundance of next generation sequencing data, however, underlines  the need to link this data with relevant epidemiological observations to derive meaningful conclusions